Optimism and pain: A positive move forward
نویسندگان
چکیده
منابع مشابه
Functional abdominal pain: time to get together and move forward.
Functional gastrointestinal disorders (FGID) include a combination of chronic or recurrent symptoms not explained by known biochemical or structural abnormalities. They represent a challenging group of conditions that are frequently misdiagnosed in children and are associated with significant morbidity and high health care costs. They account for more than 50% of the consultations in pediatric ...
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dvancing cells periodically pull on their substrates to test the environment, say Grégory Giannone, Michael Sheetz (Columbia University, New York, NY), and colleagues. The actomyosin contractions both strengthen attachments to more solid substrates, and break off part of a signaling complex so that it can be carried into the cell. Once that retrograde signal reaches myosin, which is some distan...
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Animal cells can change shape and move by using actin polymerization to drive plasma membrane protrusion. Giannone and coworkers (this issue of Cell) describe how cells periodically pull back on these protrusions in order to sense and respond to the rigidity of their environment.
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Intermediate means of transport have been presented as potential solutions to local transport and accessibility problems. However, in some situations, transport problems may be best solved through non-transport solutions (see Box 25). Where there are problems transporting water and firewood, it may be possible to create a water source nearby (a well or piped water) and reduce the demand for dis...
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Currently, the 2 main strategies for control of influenza are immunization and antiviral drugs. However, despite increasing uptake of influenza vaccine among the highest risk groups—namely, the elderly and persons with underlying cardiopulmonary diseases—morbidity and mortality from influenza continues to rise in the United States [1]. This paradox has stimulated a heated debate regarding the t...
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ژورنال
عنوان ژورنال: Pain
سال: 2013
ISSN: 0304-3959
DOI: 10.1016/j.pain.2012.10.005